Ingredient Research
Explore the Research Behind the Ingredients
We believe wellness information should be transparent. Explore published research concerning selected ingredients used in Shape Xs.
Research presented here concerns individual ingredients and should not be interpreted as clinical proof of the finished Shape Xs formulation unless a study specifically evaluated Shape Xs.
Evidence Transparency
What the Evidence Does — and Doesn't — Tell Us
Ingredient vs. Product
Studies cited here evaluated individual ingredients, often at specific doses and in specific formulations. These findings cannot automatically be applied to the finished Shape Xs multi-ingredient product.
Dose Differences
Research studies may use doses, extract concentrations or delivery forms that differ from those in Shape Xs. Results from a study using a particular dose do not necessarily predict outcomes at a different dose.
Individual Variation
Supplement responses differ between individuals based on genetics, health status, diet, activity level, age and other factors. No universal outcome can be predicted.
Lifestyle Factors Matter
Healthy weight management requires attention to overall diet, calorie intake, physical activity, sleep quality and other lifestyle factors. No supplement replaces these fundamentals.
Research Library
Published Studies by Ingredient
Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial
Heymsfield SB, Allison DB, Vasselli JR, et al.
JAMA · 1998
Population
135 overweight adults
Dosage
1500 mg HCA per day
Duration
12 weeks
Study Type
Randomised Controlled Trial
Key Findings
No significant difference in weight loss between HCA group and placebo when combined with a high-fibre, low-energy diet.
Limitations
High-fibre diet may have masked potential effects; single study.
The use of Garcinia extract (hydroxycitric acid) as a weight loss supplement: a systematic review and meta-analysis of randomised clinical trials
Onakpoya I, Hung SK, Perry R, et al.
Journal of Obesity · 2011
Population
Multiple RCTs reviewed
Dosage
Various (HCA-containing extracts)
Duration
2–12 weeks
Study Type
Systematic Review & Meta-Analysis
Key Findings
Short-term weight loss was statistically significantly greater with Garcinia extract than placebo; clinical relevance uncertain. Gastrointestinal adverse events reported more frequently in treatment groups.
Limitations
Short study durations; heterogeneous populations and doses; publication bias possible.
A dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women
Celleno L, Tolaini MV, D'Amore A, et al.
International Journal of Medical Sciences · 2007
Population
60 overweight adults
Dosage
445 mg Phaseolus vulgaris extract twice daily
Duration
30 days
Study Type
Randomised Controlled Trial
Key Findings
Significant reductions in body weight, BMI, fat mass and waist/hip circumference in the treatment group compared to placebo.
Limitations
Small sample size; short duration; industry-funded study.
Efficacy of a white bean extract as an alpha-amylase inhibitor: a meta-analysis of randomized controlled trials
Udani JK, Singh BB.
Alternative Therapies in Health and Medicine · 2004
Population
Multiple RCTs reviewed
Dosage
Various
Duration
Various
Study Type
Meta-Analysis
Key Findings
White kidney bean extract demonstrated alpha-amylase inhibitory activity; modest effects on body weight reported across studies.
Limitations
Limited number of high-quality trials; heterogeneous study designs.
Spirulina in clinical practice: evidence-based human applications
Karkos PD, Leong SC, Karkos CD, et al.
Evidence-Based Complementary and Alternative Medicine · 2011
Population
Various clinical populations
Dosage
Various
Duration
Various
Study Type
Review
Key Findings
Spirulina demonstrated antioxidant, anti-inflammatory and lipid-modulating properties in reviewed studies. Direct weight-management evidence is limited.
Limitations
Review includes heterogeneous studies; not all findings are from high-quality RCTs.
Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease
Zhang HW, Lin ZX, Tung YS, et al.
Cochrane Database of Systematic Reviews · 2014
Population
Patients with chronic kidney disease
Dosage
Various
Duration
Various
Study Type
Systematic Review
Key Findings
Some evidence of benefit for kidney function markers; evidence quality was generally low. Metabolic and energy effects noted as secondary findings.
Limitations
Studies were primarily in disease populations; generalisability to healthy adults is limited.
Aloe vera ingestion and modulation of lipid profile and body fat composition in overweight and obese subjects
Choi HC, Kim SJ, Son KY, et al.
Nutrition Research and Practice · 2013
Population
136 overweight adults
Dosage
147 mg aloe gel complex twice daily
Duration
8 weeks
Study Type
Randomised Controlled Trial
Key Findings
Significant reductions in body fat mass and body fat ratio observed in the treatment group. Effects on body weight were modest.
Limitations
Short duration; single study; further replication needed.
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