Evidence-Based Nutrition
Science You Can Trust
Every Miravion formulation is built on peer-reviewed clinical research, patented ingredient technology, and a deep understanding of the cellular biology of aging.
Our Approach
Six Pillars of Scientific Integrity
Patented Ingredients
Every active compound in ErgoNMN™ is protected by international patents — DR. ERGO™ L-Ergothioneine and Rev-AGE® NMN are not generic raw materials. They are precision-manufactured, identity-verified ingredients with documented clinical dossiers.
Peer-Reviewed Evidence
We only formulate with ingredients that have been studied in human clinical trials published in peer-reviewed journals. We do not rely on in-vitro or animal data alone.
Cellular Mechanism
Our formulations target the root biology of aging — NAD⁺ decline, mitochondrial dysfunction, and oxidative stress — rather than masking symptoms. We work at the cellular level.
Safety & Tolerability
Both DR. ERGO™ and Rev-AGE® have demonstrated excellent safety profiles in human trials. Miravion products are manufactured under GMP-certified conditions with full traceability.
Synergistic Formulation
ErgoNMN™ combines NMN and L-Ergothioneine because their mechanisms are complementary — NMN fuels NAD⁺ production while Ergothioneine protects the cellular machinery that uses it.
Transparent Disclosure
We publish our ingredient sources, dosages, and the specific studies that informed our formulation. No proprietary blends that hide effective doses.
Patented Ingredients
Two Innovations. One Formula.
Premium L-Ergothioneine
L-Ergothioneine (ERGO) is a naturally occurring amino acid and potent antioxidant. Unlike common antioxidants, ERGO is actively transported into cells via a dedicated transporter (SLC22A4), concentrating in mitochondria and nuclei — the sites most vulnerable to oxidative damage.
- Protects mitochondrial DNA from oxidative stress
- Supports healthy inflammatory response
- Accumulates in high-stress tissues (liver, kidney, brain)
- Stable under physiological conditions — not consumed in neutralising free radicals
Patented NMN
Nicotinamide Mononucleotide (NMN) is a direct precursor to NAD⁺ — a coenzyme essential for over 500 enzymatic reactions including energy metabolism, DNA repair, and sirtuin activation. NAD⁺ levels decline by up to 50% between ages 40–60, and NMN supplementation is the most clinically validated strategy to restore them.
- Directly raises blood and tissue NAD⁺ levels
- Activates sirtuins — longevity-associated proteins
- Supports mitochondrial biogenesis and energy output
- Clinically studied in multiple human RCTs
Published Research
Key Clinical Studies
A selection of peer-reviewed studies that inform our formulation decisions. Click any study to read the published research.
NMN supplementation rescues age-associated decline in NAD⁺ biosynthesis
Cell Metabolism, 2023
Oral NMN supplementation significantly elevated blood NAD⁺ levels and improved muscle insulin sensitivity in healthy adults aged 65+.
Ergothioneine as a dietary antioxidant with unique properties
Free Radical Biology & Medicine, 2022
L-Ergothioneine accumulates in mitochondria and nuclei, providing targeted protection against oxidative DNA damage and cellular stress.
Long-term NMN administration in humans: safety and efficacy
npj Aging, 2022
A 12-week randomised controlled trial confirmed NMN is safe, well-tolerated, and effectively increases NAD⁺ metabolites in healthy middle-aged adults.
Ergothioneine and cognitive health: epidemiological evidence
Biochemical and Biophysical Research Communications, 2021
Lower plasma ergothioneine levels were significantly associated with cognitive decline, suggesting a protective role in neurological aging.
NAD⁺ metabolism and its roles in cellular processes during ageing
Nature Reviews Molecular Cell Biology, 2021
Comprehensive review confirming NAD⁺ decline as a hallmark of aging and NMN as a validated precursor for restoring cellular NAD⁺ pools.
The ergothioneine transporter (ETT) and its role in cellular protection
Journal of Biological Chemistry, 2020
Cells express a dedicated ergothioneine transporter (SLC22A4), underscoring its biological importance and targeted uptake in high-stress tissues.
Ready to Begin
Put the Science to Work
Our formulations are built on the research above. Explore Shape Xs — our botanical weight-management supplement — or visit our Research page for full ingredient citations.